Lifestyle & Chronic Conditions
Defects in glycoprotein degradation
Serious
ICD-10: E77 · NIH NLM
हिंदी: ग्लाइकोप्रोटीन विघटन दोष · தமிழ்: கிளைக்கோபுரோட்டின் சிதைவு குறைபாடு · ಕನ್ನಡ: ಗ್ಲೈಕೋಪ್ರೋಟೀನ್ ವಿಘಟನೆ ದೋಷ · తెలుగు: గ్లైకోప్రోటీన్ క్షీణత లోపం · বাংলা: গ্লাইকোপ্রোটিন অবক্ষয় ত্রুটি · मराठी: ग्लायकोप्रोटीन विघटन दोष · ગુજરાતી: ગ્લાયકોપ્રોટીન ડિગ્રેડેશન ખામી
About this condition
These are rare genetic storage disorders where the body cannot properly break down complex sugar-protein molecules called glycoproteins. This causes abnormal accumulation in tissues leading to developmental delays, characteristic facial appearance, skeletal problems, and organ enlargement. Conditions like mannosidosis and fucosidosis fall in this group and require specialized genetic testing and supportive care.
Common symptoms
developmental delay
coarse facial features
bone abnormalities
enlarged liver
intellectual disability
vision problems
When to see a doctor: immediately if suspected in infant or child
This condition in Indian languages
| Hindi (हिंदी) | ग्लाइकोप्रोटीन विघटन दोष · विकास में देरी · चेहरे की विकृति · हड्डी असामान्यताएं |
| Tamil (தமிழ்) | கிளைக்கோபுரோட்டின் சிதைவு குறைபாடு · வளர்ச்சி தாமதம் · எலும்பு அசாதாரணங்கள் |
| Kannada (ಕನ್ನಡ) | ಗ್ಲೈಕೋಪ್ರೋಟೀನ್ ವಿಘಟನೆ ದೋಷ · ಬೆಳವಣಿಗೆ ವಿಳಂಬ · ಮುಖದ ವಿಕೃತಿ |
| Telugu (తెలుగు) | గ్లైకోప్రోటీన్ క్షీణత లోపం · అభివృద్ధి ఆలస్యం · ముఖ వైకల్యాలు |
| Bengali (বাংলা) | গ্লাইকোপ্রোটিন অবক্ষয় ত্রুটি · বিকাশ বিলম্ব · মুখের বিকৃতি |
| Marathi (मराठी) | ग्लायकोप्रोटीन विघटन दोष · विकासात्मक विलंब · चेहऱ्याची विकृती |
| Gujarati (ગુજરાતી) | ગ્લાયકોપ્રોટીન ડિગ્રેડેશન ખામી · વિકાસલક્ષી વિલંબ · ચહેરાની વિકૃતિ |
Frequently asked questions
What are the symptoms of Defects in glycoprotein degradation?
developmental delay, coarse facial features, bone abnormalities, enlarged liver, intellectual disability, vision problems.
When should I see a doctor?
immediately if suspected in infant or child
Is Defects in glycoprotein degradation common in India?
This condition is seen across India.
How serious is Defects in glycoprotein degradation?
Severity is classified as Serious. immediately if suspected in infant or child.
Related conditions
Important: This information is for general awareness only and is
not a substitute for professional medical advice. Always consult a qualified doctor.
In an emergency, call 112.
Data sourced from NIH NLM
and MOHFW India.
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