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Lifestyle & Chronic Conditions

Scheie's syndrome

Serious ICD-10: E76 · NIH NLM
हिंदी: शाई सिंड्रोम · தமிழ்: ஷீ சிண்ட்ரோம் · ಕನ್ನಡ: ಶೀ ಸಿಂಡ್ರೋಮ್ · తెలుగు: షీ సిండ్రోమ్ · বাংলা: শেই সিনড্রোম · मराठी: शे सिंड्रोम · ગુજરાતી: શે સિન્ડ્રોમ
About this condition

Scheie's syndrome is a rare inherited metabolic disorder where the body cannot break down certain complex sugars, causing them to build up in tissues. This leads to progressive joint stiffness, cloudy corneas, heart valve issues, and claw-like hand deformities, though intelligence remains normal. It requires lifelong specialist management.

Common symptoms
joint stiffness cloudy corneas hand deformities heart valve problems mild facial features normal intelligence
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When to see a doctor: specialist genetic counseling and ongoing monitoring required
Take action
This condition in Indian languages
Hindi (हिंदी)शाई सिंड्रोम · म्यूकोपॉलीसैकेराइडोसिस टाइप वन एस · आनुवंशिक संयोजी ऊतक रोग · जोड़ों की अकड़न रोग
Tamil (தமிழ்)ஷீ சிண்ட்ரோம் · மரபணு இணைப்பு திசு நோய் · மூட்டு விறைப்பு நோய் · கண் மூடல் மரபு நோய்
Kannada (ಕನ್ನಡ)ಶೀ ಸಿಂಡ್ರೋಮ್ · ಆನುವಂಶಿಕ ಸಂಯೋಜಕ ಅಂಗಾಂಶ ರೋಗ · ಕೀಲು ಗಟ್ಟಿತನ ರೋಗ · ಕಣ್ಣು ಮೋಡ ರೋಗ
Telugu (తెలుగు)షీ సిండ్రోమ్ · వంశపారంపర్య కలిపే కణజాల వ్యాధి · కీలు దృఢత్వ రోగం · కంటి మబ్బు రోగం
Bengali (বাংলা)শেই সিনড্রোম · বংশগত সংযোগকারী টিস্যু রোগ · জয়েন্ট শক্ত হওয়া রোগ · চোখ মেঘলা রোগ
Marathi (मराठी)शे सिंड्रोम · अनुवांशिक संयोजी ऊतक रोग · सांधे कडक होणे · डोळे ढगाळ रोग
Gujarati (ગુજરાતી)શે સિન્ડ્રોમ · વારસાગત જોડાણ પેશી રોગ · સાંધા સખત થવા રોગ · આંખ ધુંધળાપણ રોગ
Frequently asked questions
What are the symptoms of Scheie's syndrome?
joint stiffness, cloudy corneas, hand deformities, heart valve problems, mild facial features, normal intelligence.
When should I see a doctor?
specialist genetic counseling and ongoing monitoring required
Is Scheie's syndrome common in India?
This condition is seen across India.
How serious is Scheie's syndrome?
Severity is classified as Serious. specialist genetic counseling and ongoing monitoring required.
Related conditions
Important: This information is for general awareness only and is not a substitute for professional medical advice. Always consult a qualified doctor. In an emergency, call 112. Data sourced from NIH NLM and MOHFW India. Full disclaimer